What effects does HIV treatment have on cognitive performance?
Mild cognitive problems are relatively common in people with longstanding HIV infection, although in most cases are not rapidly progressive.
Goal Management training (GMT) is a cognitive therapy that has been successfully used to improve cognition in a variety of neurological conditions, as well as in healthy older people with cognitive concerns. However, the effects of this intervention in people living with HIV are unknown. The present study aims to provide evidence about whether GMT is feasible for people with cognitive concerns who are living with HIV, and whether it improves cognitive performance. This in-person intervention trains participants in techniques to improve their focus and concentration and includes exercises to improve awareness and mindfulness. Participants work in small groups with a trained therapist once a week and practice the techniques they learn at home. It is a pilot study, comparing 30 people randomly assigned to receive GMT for 7 weeks to 30 people who will be on a waitlist for that time period, and then receive GMT. Cognition will be assessed with questionnaires, and with computer tests, before starting the training, and after it is finished.