How can understanding HIV protein families help find a cure?
Dr. Cochrane’s research is unique to the HIV research community because it explores creating an HIV cure that is based on disrupting HIV gene expression and replication by manipulating the HIV-RNA process.
DNA is transcribed into RNA which is then translated into proteins by the cell. Therefore, the goal of this research is to suppress HIV gene expression with minimal effect on the cell. Understanding this process is important for the development of new approaches to controlling HIV expression and replication. Dr. Cochrane’s hopes his research project will be able to examine the effect of a select group of proteins responsible for recognizing and changing DNA involved in HIV expression. Further, Dr. Cochrane’s research will be utilized to identify and understand the differences between protein families responsible for HIV gene expression.